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Learning objectives
At the conclusion of this presentation, participants should be able to understand why are we interested in the generation of germ cells in vitro? :
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To study gametogenesis in vitro for a better understanding of this process
To study meiosis in vitro
To check the capability of human PSC (ES/iPS) to form germ cells in vitro (PGCs, male haploid-like cells and oocyte-like cells)
PSC may constitute a future source of artificial gametes for clinical studies and potential therapeutic applications
This system may provide a useful model for molecular genetic studies of human germline formation.
Conclusions and Future remarks
Lutolf et al. Nature 2009
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