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Nature, 2009
• Generation of in vitro PGC from male and female hESC
• DAZL, DAZ and BOULE promote PGC formation and germ-cell progression to meiosis and formation of haploid germ cells that ressemble round spermatids
2011
• iPSC can form in vitro meiotic and post-meiotic haploid cells over-expressing DAZ, DAZL and BOULE.
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PRECONGRESS COURSE 13 I VIENNA, AUSTRIA – 23 JUNE 2019 39
