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2012
•hESCs and iPSCs cultured in SSC conditions differentiate directly into advanced male germ cell lineages including postmeiotic,spermatid-like cells in vitro without genetic manipulation (10 days)
•hPSCs differentiated in SSC culture conditions exhibit haploid features
•Differentiation of hPSCs in SSC culture yields cells that express markers of spermatogonia, spermatocytes and spermatids
2012
Generation of PGCs/oocytes from ES/iPSCs
38
PRECONGRESS COURSE 13 I VIENNA, AUSTRIA – 23 JUNE 2019 41
