Page 52 - ESHRE2019
P. 52
Indirect comparison
• We can obtain an indirect estimate for B vs C from RCTs comparing A vs B and A
vs C:
A
B
?
C
mBC =mAC–mAB Var(mBC) = Var(mAC) + Var(mAB)
A network of trials: direct – indirect - mixed
Med B
indirect
Med C
direct
Placebo
direct
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