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RoB domains: types of bias
1. Random sequence generation (selection bias)
2. Allocation concealment (selection bias)
3. Blinding participants and personnel (performance bias)
4. Blinding outcome assessors (detection bias)
5. Incomplete outcome data (attrition bias)
6. Selective reporting (reporting bias)
7. Otherbias
Sources of bias
Selection Performance Detection Attrition Reporting
Random sequence generation Allocation concealment
Study sample
Allocation
Intervention group
Outcome assessment
Control group
Outcome assessment
Publication of study outcomes
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PRECONGRESS COURSE 17 I VIENNA, AUSTRIA – 23 JUNE 2019 45
