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Counseling
• Standard of careTotal hysterectomy (TAH) + bilateral salpingo‐oophorectomy (BSO) with or without lymphadenectomy
– 93%5‐yearsurvivalrate
– loss of reproductive potential
• Fertility‐preserving therapy is a deviation from the treatment of choice
– Demands close follow‐up and possible multiple endometrial biopsies
– Need for future hysterectomy
• Desire of childbearing vs. Oncological risks
Candidate Selection
• Grade 1 endometrial adenocarcinoma confirmed on dilation and curettage (D&C), with or without hysteroscopy
• Tumor confined to the endometrium (FIGO stage IA)
• Reproductive‐age and desire for future childbearing
• No contraindications to hormonal therapy
• Understanding of the non‐standard nature of treatment (risk of cancer)
Rodolakis A et al, Int J Gynecol Cancer 2015; 25: 1258–1265
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