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Pelvic & Abdominal Imaging
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•
Enhanced pelvic magnetic resonance imaging (MRI)
– 89%sensitivity/100%specificity
– Staging of the disease: myometrial invasion, adnexal & pelvic lymph nodes involvement
Transvaginal ultrasound
– onlyexperiencedsonographers
– comparable data with MRI for myometrial invasion evaluation
Kinkel K, et al, Radiology 1999; 212: 711–718 Vasconcelos CA, et al, J Obstet Gynaecol 2007; 27:65
DelMaschio A, et al, AJR Am J Roentgenol 1993; 160:533
Risk of synchronous ovarian cancer (25% in young women) or Lynch syndrome
Walsh C, et al, Obstet Gynecol 2005; 106:693
Fertility‐Preservation Therapy
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1. 2. 3. 4.
•
Conservative medical treatmentProgestins (PG):
Medroxyprogesterone acetate (MPA)
Megestrol acetate (MA)
Levonogestrel intrauterine device (LNG‐IUD, “Mirena”)
Combination of oral PG + LNG‐IUD
No prospective trial comparing the above regiments
Hysteroscopic resection
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