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ZIKV in semen (RNAPCR) after acute infection
Epelboin Set al. Human Reproduction Update 2017; 23(6): 629-654(review) Zika Virus and reproduction: facts, questions and current management
Red: Data from Paz‐Bailey et al, 2017 (127 index cases, 23 household contacts) Blue: Data from 15 case reports and 2 small studies (2016‐2017)
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ZIKV shedding in the genital tract
 High levels of ZIKV RNA in the acute phase
 Persistence in semen can be for several months
 variable between individuals
 Max time for ZIKV RNA after onset of symptoms 125 days  4% will have ZIKV RNA beyond this
 Shedding from vaginal tract rare and short lived  Ongoing research on:
 Frequency in asymptomatic individuals  Factors affecting genital shedding
 Frequency of sexual transmission
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PRECONGRESS COURSE 12 I VIENNA, AUSTRIA – 23 JUNE 2019 77