Cellular and molecular biology for clinical embryologists

Precongress Course 3

Embryology Special Interest Group Embryology


Course coordinators
Giovanni Coticchio (Italy), Maria José de los Santos (Spain), Carlos Plancha (Portugal), Sophie Debrock (Belgium), Susanna Apter (Finland), Debbie Montjean (France) , Roger Sturmey (United Kingdom)
 

Course type
Advanced


Course description
The course interprets through the lenses of cellular and molecular biology major processes and functions that support gamete maturation and preimplantation embryo development. Leading scientists will share with the audience their views and scientific experience on topics such as cell cycle regulation, cellular correlates of fertilization, embryo transcriptome and cell fate.
 

Target audience
Embryologists, andrologists, IVF laboratory technicians and clinicians working in reproductive medicine and science

 

Educational needs and expected outcomes

The laboratory methodologies by which human IVF is pursued are technically not demanding, well-established and widespread. However, many of the underpinning processes are often poorly understood or neglected. Therefore, the embryologist does not always have full awareness of the biological events he/she attempts to control in vitro, especially if outcomes are different from those expected. This course will propose a cellular an molecular view of crucial aspects of gametes and embryo function, offering participants an opportunity to better understand and the developmental processes that occur in the IVF laboratory.
  

Programme




Monday 01 January 1900

Chairs
Kersti Lundin, Sweden
Roger Sturmey, United Kingdom
09:00 - 09:30
Cumulus-oocyte communication determines embryonic competence through multiple signaling pathways: A Mother’s legacy
Giovanni Coticchio, Italy
09:30 - 09:45
Discussion
09:45 - 10:15
Cell cycle regulation during oocyte meiosis
Keith Jones, United Kingdom
10:15 - 10:30
Discussion
10:30 - 11:00
Coffee break
Giovanni Coticchio, Italy
Debbie Montjean, France
11:00 - 11:30
Nucleus positioning modulates gene expression in mouse oocytes
Marie Helene Verlhac, France
11:30 - 11:45
Discussion
11:45 - 12:15
A cellular view of sperm capacitation, acrosome reaction and gamete fusion
Chris Barratt, United Kingdom
12:15 - 12:30
Discussion
12:30 - 13:30
Lunch break
Cristina Magli, Italy
Sophie Debrock, Belgium
13:30 - 14:00
The choreography of fertilization and fertilization failure
Catherine Combelles, U.S.A.
14:00 - 14:15
Discussion
14:15 - 14:45
Chromosome and DNA integrity in oocytes and embryos
Eva Hoffmann, Denmark
14:45 - 15:00
Discussion
15:00 - 15:30
Coffee break
Eva Hoffmann, Denmark
Susanna Jamina Apter, Sweden
15:30 - 16:00
Mitochondrial function in oocytes and embryos
Roger Sturmey, United Kingdom
16:00 - 16:15
Discussion
16:15 - 16:45
Epigenetic pathways in cell fate regulation of the preimplantation embryo
Antoine Peters, Switzerland
16:45 - 17:00
Discussion