Ovarian Stimulation for IVF: individualisation and beyond..?

Precongress Course 6

Reproductive Endocrinology Special Interest Group Reproductive Endocrinology

Course co-ordinators
Frank Broekmans (The Netherlands)

Course type


Course description
This course will deliver up to date information on how ovarian stimulation for IVF can be optimised by individualisation, using tools such as response prediction, patient profile, choice of stimulation drug, and knowledge of the physiology of folliculogenesis.


Target audience
Reproductive endocrinologists, reproductive medicine specialists, paramedics in reproductive medicine, embryologists, IVF lab technicians.


Educational needs and expected outcomes
Currently, debates are ongoing on the value of individualised approach in ovarian stimulation for IVF. Both FSH dose, LH suppression drug and co-medication are used in this individualisation. However, solid evidence on the efficacy, costs and safety/patient burden has not been delivered. With trial results of individualised dosing having recently been published, it is the right time to consider the current evidence that could be the basement for guideline building. The proposal in draft has been put forward in the SIG RE business meeting in Lisbon, June 2015. Participants have emphasized that the need for this topic to be extensively discussed is high. Educational needs are based on several putative misconceptions in this field, such as that more is always better, that the tool FSH has an infinite dose effect relation, and that costs do not really matter. Outcomes that may be reached are improved understanding of ovarian physiology in relation to ovarian stimulation, better awareness that FSH dosages above a certain level are inappropriate, and that safety management in this field of elective medical care is prime. Direct translation into daily practice guidelines is therefore expected.


Monday 01 January 1900

Peter Humaidan, Denmark
10:30 - 11:00
Coffee break
Daniela Romualdi, Italy
11:50 - 12:00
12:20 - 12:30
12:30 - 13:30
Lunch break
Georgios Lainas, United Kingdom
13:30 - 13:50
Individualised FSH dosing: Results of the optimist and other trials
Frank J. Broekmans, The Netherlands
13:50 - 14:00
14:00 - 14:20
Management of the poor responder
Nikolaos P. Polyzos, Spain
14:20 - 14:30
14:30 - 14:50
Efficacy versus safety: Management of the high responder
Efstratios Kolibianakis, Greece
14:50 - 15:00
15:00 - 15:30
Coffee break
Sesh Kamal Sunkara, United Kingdom
15:30 - 16:10
Debate: Ovarian stimulation for IVF: One size fits all?
15:30 - 15:50
No, individualisation is mandatory
Christophe Blockeel, Belgium
15:50 - 16:10
Yes, we need to value cost efficiency
Frank J. Broekmans, The Netherlands
16:10 - 16:30
16:30 - 16:50
Freeze all, the luteal support free solution?
Anja Pinborg, Denmark
16:50 - 17:00
Discussion + Closing remarks