Recurrent implantation failure: which treatment strategies improve ART outcome?

Precongress Course 17

MEFS MEFS Exchange course

Course type

Advanced ánd Basic


Course co-ordinator(s)
Johnny Awwad (Lebanon) and Mohammad Aboulghar (Egypt)

Course description
Although advances in the field of Assisted Reproduction have improved significantly the reproductive outcome for infertile couples, a riddle nonetheless remains which is the management of women with recurrent implantation failure (RIF). Repeat cycle failures can leave couples scarred and desperate for solutions. RIF is a complex condition with a wide variety of uncertain etiologies and very often highly controversial treatment options.
This precongress course discusses some of these practices and their impact on the success of IVF/ICSI in view of emerging scientific evidence.

Target audience

  • Reproductive Endocrinologists and Fertility Specialists
  • Biologists involved in Assisted Reproductive Technologies
  • Policy Regulators and Representatives of Third Party Payer

Educational needs and expected outcomes 

At the completion of this precongress course, participants should be able to:

  • Describe the mechanisms involved in embryo implantation and implantation failure in IVF/ICSI cycles.
  • Appraise the literature regarding the cost-effectiveness of common practices in the management of recurrent implantation failure on the basis of the evidence.
  • Develop an evidence-based decision tree on when and if these interventions are efficacious and medically indicated.


Monday 28 June 2021

Session 1
Mohamed Aboulghar, Egypt
09:00 - 09:30
Endometrial receptivity and implantation failure
Nicholas Macklon, Denmark
09:30 - 09:45
09:45 - 10:15
Systematic endometrial injury: A tool of the past?
Mohamed Aboulghar, Egypt
10:15 - 10:30
10:30 - 11:00
Coffee break
Session 2
Michel Abou Abdallah, Lebanon
11:00 - 11:30
Preimplantation Genetic Testing for Aneuploidy (PGT-A): Is intervention useful at all?
Elias Dahdouh, Canada
11:30 - 11:45
11:45 - 12:15
Dissociation of follicular endometrial events: To freeze or not to freeze?
Christos Venetis, Australia
12:15 - 12:30
12:30 - 13:30
Lunch break
Session 3
Johnny Awwad, Lebanon
13:30 - 14:00
Luteal endometrial manipulation other than progesterone: What is out there? [GnRHa stimulation, intrauterine hCG perfusion, autologous intrauterine platelet-rich plasma and granulocyte colony-stimulation factor]
Yacoub Khalaf, United Kingdom
14:00 - 14:15
14:15 - 14:45
Endometrial genomic signature and personalized embryo transfer: Is timing everything?
Nicholas Macklon, Denmark
14:45 - 15:00
15:00 - 15:30
Coffee break
Session 4
Mohamed Aboulghar, Egypt
15:30 - 16:00
The role of LMWH: Where is the evidence?
Johnny Awwad, Lebanon
16:00 - 16:15
16:15 - 16:45
Endometrial immune modulation: Facts or Fads? [IVIG, Intralipids and steroids]
Yacoub Khalaf, United Kingdom
16:45 - 17:00