Much research in oncofertility is dedicated to the preservation of gametes and thereby the generation of genetically linked offspring after gonodotoxic treatments. As females are born with primordial follicles in their ovaries, fertility preservation and restoration in females is already clinically applied and children born from cryopreserved and grafted ovarian cortex or cryopreserved oocytes and embryos. Males are not born with mature gametes, but their gonads contain spermatogonial stem cells, which require a very specialised process of spermatogenesis (with critical steps of mitotic and meiotic divisions) for viability. This gamete production begins at puberty. This difference between males and females requires alternative approaches in oncofertilty, which, although in their preclinical phase, have made fair progress towards clinical use.
According to the latest findings, various avenues are now under investigation for the restoration of male fertility against the effects of oncological treatments or other fertility-compromising diseases.
This Campus course will discuss our most recent understanding of this progress, giving special emphasis to the most challenging steps in stem cell maintenance and sperm development in vitro and/or transplantation.
The course consists of plenary sessions on the translation of crucial steps in sperm development from animal models and their implication for future clinical application. The sessions will provide an excellent update on the latest technologies in male fertility preservation and restoration, and a look at current European initiatives.
All clinicians, biologists, scientists, IVF laboratory technicians and paramedicals interested in fertility preservation.
Interest in male reproduction and spermatogenesis
This 1.5 day workshop will offer plenty of time for discussion and exchange of information. Our Campus course in Paris in 2016 was on fertility preservation in females. Now we switch our attention to the male, which requires quite different oncofertility approaches. This course will also be the first of the newly established SIG Fertility Preservation. Registered participants will be given access to the ESHRE learning/teaching zone. Emphasis would be on clinical basics with the addition of cutting-edge molecular research.
The official language of the course is English.
Participants can only obtain a certificate of attendance after completing the online evaluation. After the course, ESHRE will send an e-mail with the link and more information.