Guideline on Controlled Ovarian Stimulation in IVF/ICSI


Reproductive Endocrinology 
Responsible Special Interest Group: 
SIG Reproductive Endocrinology 


Current status of the guideline:
 (last update: 12/02/2019) 
Open for stakeholder review until 26 March 2019

Scope of the guideline:

Ovarian stimulation is an integral part of assisted reproductive techniques. Ovarian stimulation is employed to induce development of multiple dominant follicles, and to mature more oocytes to improve chances for conception. The aim of this ESHRE guidelines project is to provide gynecologists, medical physicians and embryologists in the field of reproductive medicine, infertility and assisted reproduction with evidence-based information on the different options for Ovarian Stimulation in IVF/ICSI. Optimal ovarian response, live birth rates, safety, patient compliance and individualization will hereby be taken into account. A guideline group has been established (with many European experts) and 20 key questions formulated. Following a literature search, evidence will be graded and recommendations formulated.

Draft guideline now open for stakeholder review

The COS working group is proud to present the draft for the ESHRE Guideline on Controlled ovarian stimulation for IVF/ICSI, which provides recommendations on investigations, recommended treatments and prevention of OHSS. The document will be open for stakeholder review until 26 March 2019.
We would like to invite you to submit your comments. 

We welcome every comment to the guideline: you can either look at the summary of recommendations and comment on the comprehensiveness, clarity and applicability of the recommendations, but you can also review the entire guideline or only one section of special interest to you.

The procedure is as follows:

  1. Read the draft version:
    Download the document "ESHRE Guideline on Controlled ovarian stimulation for IVF/ICSI

  2. Submit your comments:
    To submit your comment, please complete the review form and send it to guidelines@eshre.eu before 26 March 2019.

  3. All comments will be listed in the review report, with a response of the working group. If relevant, the guideline recommendations will be altered. If no change is made, the reasons for this will also be recorded. The review report will be published on the ESHRE website, and all reviewers will be listed in Annex 6 of the guideline.