Chromosomal mosaicism in human embryos: Incidence, prevalence, diagnostic possibilities and clinical management in PGT-A cycles
Precongress Course 10
Special Interest Group Reproductive Genetics
Course type
Advanced
Course Co-ordinators
Georgia Kakourou (Greece), Claudia Spits (Belgium), Antonio Capalbo (Itlay), Francesco Fiorentino (Italy), Filippo Zambelli (Italy)
Course description
The course will provide a preliminary overview about the human aneuploidies , provide an update on existing data on the mosaicism features in the preimplantation, prenatal and postnatal period, detailed information about the detection possibilities and clinical management of chromosomal mosaicism in PGT-A cycles.
Target audience
Reproductive geneticists, embryologists, gynaecologists, researchers, ethicists and professionals working in ART and reproductive medicine
Educational needs and expected outcomes
The rapid developments in molecular genetics, including advanced technologies and a wealth of data that have been obtained particular in the last years demand to inform clinicians, embryologists, geneticists and all involved in ART on the relevance and clinical application of information. The course will provide an overview in a series of lectures by experts in the field and by offering a platform for discussions and interactions between participants and faculty.
Programme
Sunday 23 June 2019
09:00 - 17:00
PCC10: Chromosomal mosaicism in human embryos: Incidence, prevalence, diagnostic possibilities and clinical management in PGT-A cycles
Sunday 23 June 2019
09:00 - 17:00: PCC10: Chromosomal mosaicism in human embryos: Incidence, prevalence, diagnostic possibilities and clinical management in PGT-A cycles:
Dagan Wells, United Kingdom
09:00 - 09:30
Aneuploidies in human gametes and embryos
09:45 - 10:15
Risk factors and molecular mechanisms contributing to mosaicism in embryos
10:30 - 11:00
Coffee break
11:00 - 11:30
The fate of aneuploid cells in mosaic embryos
Shruti Singla, United Kingdom
11:45 - 12:15
Prevalence and typology of mosaicism in POCs and pregnancies
12:30 - 13:30
Lunch break
Francesco Fiorentino, Italy
13:30 - 14:00
Methodologies to study mosaicism in embryos
14:15 - 14:45
Prevalence of chromosomal mosaicism in IVF derived embryos
Dagan Wells, United Kingdom
15:00 - 15:30
Coffee break
15:30 - 16:00
Impact of chromosomal mosaicism in IVF outcomes
Francesca Spinella, Italy
16:15 - 16:45
Chromosomal mosaicism in non-invasive PGT-A
Carmen Rubio LLuesa, Spain