Endocrine disease and male fertility: from childhood to adulthood

Precongress Course 1

Andrology    Special Interest Group Andrology

Course coordinators

Nathalie Rives (France), Michael Carroll (United Kindgom), Nicolas Garrido Purchalt (Spain), Ellen Goossens (Belgium), Francesco Lotti (Italy), Aldona Mzyk (The Netherlands)

Course type



Course description

The spermatogenesis is a highly biological process initiated during the embryonic development of the testis. The regulation of spermatogenesis involves both endocrine and paracrine regulators. Endocrine regulators come not only from the gonadotrophic axis but also other endocrine glands. Consequently, endocrine pathologies (acquired or congenital) can affect testicular functions. This course will address interesting questions on environmental, metabolic and endocrine factors susceptible to modulate or impair spermatogenesis and consequently male fertility.


Target audience

Andrologists, Urologists, Embryologists, Reproductive Endocrinologists, Pediatric Endocrinologists, Clinicians in Reproductive Medicine, Basic scientists in Reproductive Medicine and Reproductive Geneticists


Educational needs and expected outcomes 

At the end of the course, the participants should be able to:

  • Understand the physiology and physiopathology of the testis development
  • Acquire knowledge on congenital endocrine diseases that can impair semen parameters and male fertility
  • Acquire knowledge on acquired endocrine disease that can impair semen parameters and male fertility
  • Summarize the potential interventions to assist infertile males with endocrine disease



Friday 23 June 2023

Ellen Goossens, Belgium
Aldona Mzyk, The Netherlands
Session 1: A deeper view of testis physiology
09:00 - 09:30
Development and regulation of the testis : from fetal life to adulthood
Rod Mitchell, United Kingdom
09:30 - 10:00
Evolution of semen parameters from puberty to adulthood: are there normal references for adolescents?
Niels Jorgensen, Denmark
10:00 - 10:30
10:30 - 11:00
Coffee break
Ellen Goossens, Belgium
Francesco Lotti, Italy
Session 2: Hormonal disease and male fertility
11:00 - 11:30
Congenital and acquired hypogonadotropic hypogonadism: induction of spermatogenesis at puberty, impact on future fertility
Michael Carroll, United Kingdom
11:30 - 12:00
Gonadal dysfunction in males with congenital adrenal hyperplasia
Hedi L. Claahsen-van der Grinten, The Netherlands
12:00 - 12:30
12:30 - 13:30
Lunch break
Francesco Lotti, Italy
Ellen Goossens, Belgium
Session 3: Testicular disease and future fertility
13:30 - 14:00
Cryptorchidism: when and how to treat, consequences on future fertility
Jorma Toppari, Finland
14:00 - 14:15
14:15 - 14:45
Klinefelter syndrome and fertility in adulthood
Nathalie Rives, France
14:45 - 15:00
15:00 - 15:30
Coffee break
Nicolás Garrido Puchalt, Spain
Michael Carroll, United Kingdom
Session 4: External endocrine disruptors, metabolism and male fertility
15:30 - 15:50
Obesity, bariatric surgery and male fertility
Francesco Lotti, Italy
15:50 - 16:00
16:00 - 16:20
Endocrine disruptors and male fertility
Florence Eustache, France
16:20 - 16:30
16:30 - 17:00
Discussion of all content of the day / Round table