ESHRE Webinar

organised by the ESHRE Special Interest Group Stem Cells

Course description

This webinar will present the first attempt at 'reverse engineering' the human ovary. Using this concept, researchers have deconstructed the microenvironment of human ovarian cells to better understand their proteomic, architectural, and mechanical cues, as well as their role in ovarian activity. The goal is to reintegrate this knowledge into a biomimetic construct, a transplantable engineered ovary (TEO) that could restore fertility in cancer survivors who have impaired fertility. By integrating these data, the TEO could potentially become a life-changing option for many female patients.

Target audience

Clinicians, scientists and researchers with an interest in bioengineering

Needs assessment

Based on the needs assessment process, the derived educational needs for the webinar could include:

• Familiarity with tissue engineering principles and their application in the field of reproductive medicine
• Knowledge of the concept of reverse engineering in biology and its relevance to the development of a transplantable engineered ovary
• Understanding the microenvironment (matrisome) of human ovarian cells and its role in ovarian activity across different life stages

Expected educational outcomes

• Enhanced comprehension of tissue engineering principles and their application in the development of a transplantable engineered ovary (TEO)
• Familiarity with the concept of reverse engineering in biology and its relevance to the understanding and re-engineering of the human ovary
  - Comprehensive knowledge of the microenvironment (matrisome) of human ovarian cells, including its proteomic, architectural, and mechanical cues, and their role in ovarian activity throughout a woman's life

Programme

17:00 - 17:05 Introduction by Christiani Amorim
17:05 - 17:45 Presentation by Emna Ouni
17:45 - 18:10 Q&A by Christiani Amorim

Practicalities

Participants can obtain a certificate of attendance after watching the webinar on the eCampus platform here.